The Optimal Immunity Support Pack combines six products for complete six-dimensional immune health — Immunocal® for glutathione, Immunocal Booster® for Nrf2 activation, Probio 3+ With Cranberry for the gut-immune axis, Multi+ Resveratrol for micronutrient completeness, Omega Gen V 5-in-1 for anti-inflammatory support, and K-21+ Sugar Free for adaptogenic stress resilience. The most comprehensive immune support bundle in the Immunotec range. 30-day supply of each. Available worldwide.

(4 customer reviews)

$209.25

Optimal Immunity Support Pack — Six Products. Six Dimensions of Immune Health. One Complete Daily Protocol.

Modern immunology has fundamentally changed how researchers understand immune health. The old model treated the immune system as a single entity — you either had good immunity or you did not. The current model recognizes immune function as a multi-dimensional system where six distinct but interconnected foundations must all be operating effectively for genuine, comprehensive immune resilience: the intracellular antioxidant foundation, the gene-level antioxidant amplification, the gut microbiome that houses 70% of immune tissue, the micronutrient and polyphenol completeness that every immune process depends on, the omega-3 anti-inflammatory environment that allows immune responses to be precise rather than chronic, and the stress resilience that prevents the cortisol-driven immune suppression that modern life constantly threatens.

The Optimal Immunity Support Pack addresses all six simultaneously — assembling the six Immunotec products that together cover every dimension of immune health that research has identified as critical. Immunocal® raises glutathione — the cellular immune foundation. Immunocal Booster® activates Nrf2 — the antioxidant gene amplifier. Probio 3+ With Cranberry supports the gut microbiome — the physical home of immune tissue. Multi+ Resveratrol provides micronutrient completeness and longevity polyphenol support. Omega Gen V delivers omega-3 anti-inflammatory protection. K-21+ Sugar Free provides adaptogenic stress resilience that protects the immune system from the most common modern threat to its function. This is the most comprehensive immune support bundle in the Immunotec range — and the most intelligently assembled.

What Is Inside the Optimal Immunity Support Pack

Immunocal® — The Glutathione Immune Foundation

Immunocal® is where immune health in the Immunotec system begins and where it is most deeply rooted. Approximately 70% of the body's immune tissue is located in and around the gastrointestinal tract — and the immune cells throughout this system, along with every other immune cell in the body, require adequate intracellular glutathione to function at full capacity.

T-lymphocyte proliferation — the clonal expansion of immune cells in response to antigenic challenge — is directly dependent on intracellular glutathione levels. Natural killer cell cytotoxicity — the ability to identify and eliminate virally infected and abnormal cells — correlates with glutathione availability. Dendritic cells require glutathione for optimal antigen presentation. The entire adaptive immune response — the targeted, specific immune defense that develops memory and protects against future challenge — is impaired by glutathione depletion.

Immunocal® raises intracellular glutathione through its patented Bonded Cysteine™ technology — delivering undenatured whey protein isolate that preserves the disulfide bonds protecting cysteine through digestion, allowing it to reach cells intact for glutathione synthesis. This mechanism is protected by 79 international patents, validated by 90+ peer-reviewed clinical studies in human subjects, and recognized with listings in both the US Physicians' Desk Reference and the Canadian Compendium of Pharmaceuticals and Specialties. It is the non-negotiable foundation of the Optimal Immunity Support Pack — the cellular immune substrate that everything else in this bundle is designed to support and amplify. 30 pouches.

Immunocal Booster® — Nrf2 Gene Activation for Amplified Protection

The Immunocal Booster® is the product that takes the glutathione foundation of Immunocal® and activates the gene-level system that makes it maximally effective — completing the first critical pairing in the Optimal Immunity Support Pack.

When sulforaphane from broccoli seed extract activates the Nrf2 pathway, cells upregulate the full coordinated network of protective enzyme genes simultaneously — including the glutathione synthesis enzymes that increase production capacity from the precursors Immunocal® delivers, the glutathione peroxidase that deploys glutathione against hydrogen peroxide and lipid hydroperoxides, superoxide dismutase and catalase for first-line free radical defense, and a broad array of detoxification and cellular protective proteins. Selenium in the Booster provides the cofactor that glutathione peroxidase requires to function — bridging the glutathione precursor supply from Immunocal® to the enzymatic deployment system that Nrf2 activates.

The 50+ phytonutrients from organic fruits and vegetables in the Reds and Greens complex add the dietary antioxidant and anti-inflammatory breadth that gene-level protection alone does not provide — delivering the polyphenol and phytonutrient diversity that a complete immune health protocol requires alongside its cellular foundation. Gluten-free, vegan, sugar-free. 30 stick packs.

Probio 3+ With Cranberry — The Gut-Immune Axis

The gut microbiome is not merely a digestive system — it is the physical infrastructure of the immune system. The gut-associated lymphoid tissue — Peyer's patches, mesenteric lymph nodes, and the lamina propria — contains more immune cells than any other tissue in the body. These cells monitor the intestinal contents continuously, distinguishing between harmless dietary antigens and genuine pathogens, and communicating with the systemic immune system through a constant stream of cytokines, secretory IgA, and gut-derived immune signals.

The composition of the gut microbiome directly determines how effectively this immune monitoring system operates. A balanced, diverse microbiome with adequate populations of Lactobacillus and Bifidobacterium strains produces short-chain fatty acids that nourish colonocytes, strengthens the intestinal barrier that prevents pathogen translocation into systemic circulation, and stimulates the balanced immune signaling that keeps immune responses appropriate and controlled. A depleted or imbalanced microbiome produces the opposite — a compromised barrier, dysregulated immune signaling, and the chronic low-grade inflammation that impairs immune precision.

Probio 3+ With Cranberry delivers seven probiotic strains from Lactobacillus and Bifidobacterium families at 5 billion live CFUs, organic prebiotics FOS and inulin to nourish and sustain them, and cranberry extract for additional antioxidant and urinary health support. In the context of the Optimal Immunity Support Pack, Probio 3+ addresses the gut-immune axis — the dimension of immune health that the glutathione and Nrf2 products cannot reach — providing the microbiome support that underlies the immune tissue health that every other product in this bundle ultimately depends on. 30 capsules.

Multi+ Resveratrol — Micronutrient Completeness and Longevity Polyphenol Support

Immune function is a metabolically intensive, micronutrient-dependent set of processes. Vitamin A supports mucosal barrier integrity — the first line of defense against pathogen entry. Vitamin C drives neutrophil function, collagen synthesis for wound healing, and antioxidant recycling alongside glutathione. Vitamin D — which requires a separate mention in the context of immune regulation — directly regulates innate and adaptive immune gene expression. B vitamins support the energy metabolism that immune cell proliferation and antibody production demand. Zinc supports hundreds of immune-related enzyme functions and is essential for T-cell development. Iron supports red blood cell production and oxygen delivery. The trace elements provided by chlorella — many too numerous to formulate individually — serve as cofactors for dozens of immunologically relevant enzymes.

Multi+ Resveratrol provides the 13-vitamin, 5-mineral foundation that covers these micronutrient requirements, combined with chlorella for the complete trace element spectrum and resveratrol — the polyphenol antioxidant that activates sirtuin longevity genes, reduces NF-kB-driven inflammatory signaling, and provides cardiovascular and cellular protective benefits that extend the immune health foundation into the aging and longevity dimension. No other multivitamin in the Immunotec range combines this level of nutritional completeness with the polyphenol and trace mineral additions that make Multi+ Resveratrol the most comprehensive daily micronutrient foundation available. 2 capsules daily. 30-day supply.

Omega Gen V — Anti-Inflammatory Environment for Precise Immune Function

An immune system operating in a chronically inflamed environment is an immune system under continuous misdirected activation — consuming resources, generating collateral tissue damage, and failing to distinguish between genuine threats and background inflammatory noise. Chronic low-grade inflammation is one of the most significant impairments to immune precision and resilience in the modern population, driven primarily by omega-3 deficiency, poor dietary quality, and the constant inflammatory stimulation of modern life.

Omega Gen V's 1,800mg of EPA and DHA from Peruvian cold-water fish oil directly addresses this inflammatory environment — EPA reducing pro-inflammatory eicosanoid production through COX and LOX pathway inhibition, DHA incorporating into cell membranes to reduce their inflammatory signaling responsiveness. Turmeric's curcumin adds NF-kB inhibition and cytokine modulation through complementary mechanisms. CoQ10 supports the mitochondrial energy production that immune cells require for activation, proliferation, and the sustained effort of mounting an effective immune response. Piperine maximizes the bioavailability of both turmeric and CoQ10. Vitamin E protects the omega-3 fatty acids themselves from oxidation while providing fat-soluble membrane antioxidant protection throughout the body.

In the Optimal Immunity Support Pack, Omega Gen V provides the anti-inflammatory environment that allows the immune system supported by glutathione, Nrf2, gut health, and micronutrients to respond with precision and efficiency rather than chronic misdirected activation. 4 softgels daily. 30-day supply.

K-21+ Sugar Free — Adaptogenic Stress Resilience for Immune Protection

Cortisol — the primary stress hormone — is one of the most potent known immunosuppressants. Chronic psychological and physical stress elevates cortisol continuously, suppressing natural killer cell activity, reducing T-cell proliferation, impairing antibody production, and blunting the entire adaptive immune response. This is not a subtle effect — research consistently shows that chronically stressed individuals have significantly impaired immune responses to vaccination, higher rates of infection, and slower recovery when illness does occur. No immune support protocol is complete without addressing the stress-immune connection.

K-21+ Sugar Free addresses this through its 21-herb adaptogenic formula anchored by Rhodiola rosea root — one of the most clinically validated adaptogenic botanicals for cortisol modulation, stress resilience, and the HPA axis regulation that keeps the stress response proportionate rather than chronic. Rhodiola has been shown in clinical research to reduce cortisol levels under stress, improve physical and mental performance in fatigued individuals, and support the immune recovery that stress suppression impairs. The 21-herb formula adds the mineral electrolyte complex, iodine for thyroid and immune function, and the full adaptogenic breadth that no single-herb formula can provide.

The sugar-free formulation of K-21+ in this bundle eliminates the concern that some users have about sugar in the standard K-21+ — delivering the same complete adaptogenic formula without any impact on blood sugar, making it fully compatible with ketogenic, diabetic-friendly, and calorie-controlled dietary approaches. In the context of the Optimal Immunity Support Pack, K-21+ Sugar Free addresses the lifestyle dimension of immune health — protecting the immune system from the most pervasive modern threat to its function. Liquid formula. 30-day supply at recommended dose.

The Six Dimensions of Immune Health Covered by the Optimal Immunity Support Pack

Cellular antioxidant foundation — Immunocal®: Raises intracellular glutathione so immune cells have the antioxidant capacity to function, proliferate, and respond effectively.

Gene-level antioxidant amplification — Immunocal Booster®: Activates Nrf2 to upregulate the full protective enzyme network, amplifying the glutathione system and providing sustained gene-level immune support.

Gut microbiome and gut-immune axis — Probio 3+ With Cranberry: Nourishes the gut-associated lymphoid tissue that houses 70% of the immune system through probiotic, prebiotic, and antioxidant cranberry support.

Micronutrient completeness and longevity polyphenols — Multi+ Resveratrol: Provides every vitamin, mineral, and trace element that immune processes require, alongside resveratrol for longevity gene support and anti-inflammatory activity.

Anti-inflammatory environment — Omega Gen V: Creates the precise, low-inflammation internal environment that allows immune responses to be targeted and effective rather than chronic and depleting.

Stress resilience — K-21+ Sugar Free: Protects the immune system from cortisol-driven suppression through adaptogenic HPA axis support that preserves immune function under modern life's stress demands.

How to Use the Optimal Immunity Support Pack

Morning with Immunocal® serving: Mix one Immunocal® pouch with 6 oz of cold water in a shaker cup. Mix one Immunocal Booster® stick pack with 6 oz of cold water alongside it. Take two Multi+ Resveratrol capsules and four Omega Gen V softgels with breakfast. Take one Probio 3+ With Cranberry capsule with breakfast.

K-21+ Sugar Free: Take as directed — typically one serving in the morning or mid-morning, diluted in water. K-21+ Sugar Free is the liquid adaptogenic tonic that supports energy, stress resilience, and the thyroid and adrenal function that immune health depends on throughout the day.

All products are 30-day supplies at their recommended serving sizes.

What Is Included

One box Immunocal® — 30 pouches. One box Immunocal Booster® — 30 stick packs. One box Probio 3+ With Cranberry — 30 capsules. One box Multi+ Resveratrol — 60 capsules, 30-day supply. One bottle Omega Gen V — 120 softgels, 30-day supply. One bottle K-21+ Sugar Free — 30-day supply. All six products provide a coordinated 30-day Optimal Immunity Support protocol. Available worldwide with global shipping.

4 reviews for Optimal Immunity Support Pack Six Product Bundle

  1. Eleanor Whitfield

    I have been building my Immunotec routine piece by piece over the past year and this pack brought it all together in one go. The combination of six products covering every angle of immune health is exactly what I was working toward. After two months on the full protocol my energy is the best it has been in a decade, I have not had a single cold or infection, and my overall sense of wellbeing is genuinely different. The K-21 for stress support alongside the glutathione and gut health products covers everything modern life throws at the immune system. Absolutely worth it.

  2. Victor

    Six products, six dimensions of immune health, one order. The logic is airtight and the results are real. Two months in and I feel genuinely protected from the inside out. Best investment in my health I have made.

  3. Miriam Johansson

    I was already taking Immunocal and the Booster and decided to complete the protocol with this full pack. Adding the probiotic, multivitamin, omega-3 and K-21 to my routine made a noticeable additional difference. My digestion improved, my mood is more stable, my stress response is better, and my immune system feels genuinely robust. The comprehensiveness of this approach is what makes it work. You cannot support immune health with just one product and this bundle understands that. Highly recommend for anyone serious about long term immune resilience.

  4. Brian M.

    Ordered this after a particularly rough winter where I kept getting sick. Three months on the full protocol and I have not been sick once. The combination of gut support from the probiotic, stress resilience from K-21, and the core glutathione system from Immunocal and the Booster covers every weak point I had. This is the most complete supplement routine I have ever followed and the price for six products together is very reasonable.

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